Linking Self-Control to Negative Risk-Taking Behavior among Chinese Late Adolescents: A Moderated Mediation Model.

Negative risk-taking behaviors refer to voluntary behaviors that lead to more harm than good. Low self-control is a crucial predictor of adolescents' negative risk-taking behavior, but its internal mechanisms require further exploration. To reveal the working process underlying the association between self-control and adolescents' negative risk-taking behaviors, we investigated the mediation of regulatory focus and the moderation of sense of power. A total of 2018 students (37.6% males) from two universities in Guangzhou, China, participated in a survey that investigated their self-control, negative risk-taking behavior, regulatory focus and sense of power. The results revealed that after controlling for the adolescents' sex and their parents' educational level, prevention focus partially mediated the association between self-control and negative risk-taking behavior. Moreover, sense of power moderated the association between self-control and prevention focus. Furthermore, the association between self-control and negative risk-taking behavior through prevention focus was stronger among adolescents with a high sense of power than among those with a low sense of power. Therefore, our findings suggest that regulatory focus and sense of power might be the mechanisms that explain how self-control is related to negative risk-taking behavior. These results thus provide a foundation for the prevention of and intervention in adolescents' negative risk-taking behavior.

Engaging in prosocial behavior explains how high self-control relates to more life satisfaction: Evidence from three Chinese samples.

High levels of self-control are found to be associated with greater life satisfaction. To further understand this relationship, the current study examined two questions: (1) whether too much self-control reduces, rather than increases, life satisfaction, as argued by some scholars; and (2) whether engaging in prosocial behavior explains the "self-control-life satisfaction" link. To this end, we conducted survey research among adolescents (N = 1,009), university students (N = 2,620), and adult workers (N = 500). All participants answered the same self-control and life satisfaction measures, whereas prosocial behavior was assessed using different scales across samples. Results of two-line regressions failed to reveal significant inverted-U shaped association between self-control and life satisfaction across samples. Moreover, results of mediation analyses showed that across samples, high levels of self-control were related to greater life satisfaction and this association was partly mediated by prosocial behavior. In conclusion, there is no evidence showing that too much self-control impairs life satisfaction. Engaging in prosocial behavior partly explains how high self-control relates to greater well-being.

In vitro porcine brain tubulin assembly inhibition by water extract from a Chinese medicinal herb, Tripterygium hypoglaucum Hutch.

AIM: To investigate the effect of Tripterygium hypoglaucum Hutch (THH) on the assembly and disassembly process of tubulin and its possible mode of action. METHODS: In vitro porcine brain tubulin assembly assay was employed to analyze the inhibitory effects of THH at different concentrations (0.05 microg/L, 0.07 microg/L, 0.09 microg/L). Colchicine (0.0025 mmol/L, 0.0050 mmol/L, 0.0075 mmol/L) was used as a positive control. RESULTS: THH could significantly inhibit the assembly of isolated porcine brain tubulin at all tested concentrations. CONCLUSION: THH is capable of inducing aneuploidy in mammals via tubulin polymerization inhibition pathway and may pose a genetic risk to human beings.